IP3KA siRNA h, shRNA and Lentiviral Particle Gene Silencers
Results. Inositol-trisphosphate 3-kinase A gene (ITPKA), a kinase 5 Jan 2021 In contrast, ITPKA is expressed primarily in neurons, while ITPKC expression is restricted to glia (27). qPCR analysis of ITPKA, ITPKB, and ITPKC In lung and breast cancer expression of ITPKA is stimulated by gene body methylation which 23 Feb 2021 GAPDH gene was the internal control for ITPKA. Primers for ITPKA was designed based on GenBank reference sequence (Genebank Key Words: Human cumulus cell, gene expression, oocyte quality, pregnancy, live birth and HSD3B1) and the calcium-related genes (TRPM7, ITPKA,. PTHLH suppresses expression of neuronal genes in nonneuronal tissues, regulates expression of ITPKA. Knockdown of REST/NRSF induced expression of ITPKA in 5 Mar 2021 ITPKA (Inositol-Trisphosphate 3-Kinase A) is a Protein Coding gene. Among its related pathways are superpathway of inositol phosphate 2 May 2019 Filtering for genes in which 3'UTR DNA methylation strongly correlated with Methylation of the ITPKA gene body is associated with increased (B) Fold change of mRNA expression of genes with DNA hypermethylated DMRs following BDPP administration; GRB10,.
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Results: Inositol-trisphosphate 3-kinase A gene (ITPKA), a kinase with limited tissue distribution, was identified as a potential oncogene. We showed that ITPKA expression is up-regulated in many forms of cancers, including lung and breast cancers, and that overexpressed ITPKA contributes to tumorigenesis. ITPKA - Inositol-trisphosphate 3-kinase A - Homo sapiens (Human) - ITPKA gene & protein UniProtKB - P23677 (IP3KA_HUMAN) ITPKA (inositol-trisphosphate 3-kinase A) ITPKA DrugBank Gene Name P23677 UniProt Accession 3706 Entrez Gene Id Gene Info: Publications: Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Itpka - Inositol-trisphosphate 3-kinase A - Rattus norvegicus (Rat) - Itpka gene & protein UniProtKB - P17105 (IP3KA_RAT) Itpka Gene Detail Summary Symbol. Itpka Name.
ITPKA. Gene descriptioni.
tr A0JBZ9 A0JBZ9_BOVIN Bucentaur-2 OS=Bos taurus GN
Among its related pathways are superpathway of inositol phosphate compounds and Metabolism . Gene Ontology (GO) annotations related to this gene include calmodulin binding and calmodulin-dependent protein kinase activity . ITPKA is a potential oncogene that it is overexpressed in most tumors, and its overexpression promotes tumorigenesis. ITPKA gene body methylation regulates its expression and thus serves as a novel and potential biomarker for early cancer detection.
Grafting data - Rshiny server for NBIS
(1992) mapped the ITPKB gene to 1q41-q43.
This enzyme helps add a cluster of oxygen and phosphorus atoms (a phosphate group) to a molecule called Ins(1,4,5)P3 to produce a molecule called Ins(1,3,4,5)P4. Inositol 1,4,5-trisphosphate 3-kinase C (ITPKC) is the last identified member of the inositol 1,4,5-trisphosphate 3-kinases… Expand
ITPKA Gene Body Methylation Regulates Gene Expression and Serves as an Early Diagnostic Marker in Lung and Other Cancers. Wang YW, Ma X, Zhang YA, Wang MJ, Yatabe Y, Lam S, Girard L, Chen JY, Gazdar AF. J Thorac Oncol. ITPKA gene product. IP3-3KA, IP3KA. Regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4.
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ITPKA gene body methylation regulates its expression and thus serves as a novel and potential biomarker for early cancer detection.
Distinct expression in astrocytes and processes in CNS.
The product SIRGT96128WQ-2OMe is a type of small interfering RNA (siRNA) that targets Itpka gene and regulates the expression of gene. The siRNA interferes with the expression of Itpka gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. Next-day shipping cDNA ORF clones derived from ITPKA inositol-trisphosphate 3-kinase A available at GenScript, starting from $99.00. Gene views which provide displays for data associated at the gene level such as orthologues, paralogues, regulatory regions and splice variants.
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Gene ID Unique ID sequence Human GeCKOv2 A number
ITPKA gene, which is located in 15q15, encodes a predicted 461 amino acid polypeptide. Under physiological conditions, ITPKA is only identified in neurons and testis [ 6 ]. Plasmid pCNL-N1_ITPKA from Dr. Yasushi Okada's lab contains the insert inositol triphosphate 3-kinase A and is published in Proc Natl Acad Sci U S A. 2015 Apr 7;112(14):4352-6. doi: 10.1073/pnas.1418468112.
MIKKELSEN_MCV6_HCP_WITH_H3K27ME3 # Genes with
Under physiological conditions, ITPKA is only identified in neurons and testis [ 6 ]. Plasmid pCNL-N1_ITPKA from Dr. Yasushi Okada's lab contains the insert inositol triphosphate 3-kinase A and is published in Proc Natl Acad Sci U S A. 2015 Apr 7;112(14):4352-6. doi: 10.1073/pnas.1418468112. The Parkinson’s disease-associated gene ITPKB protects against α-synuclein aggregation by regulating ER-to-mitochondria calcium release Daniel J. Apiccoa,b,1 , Evgeny Shlevkova, Catherine L. Nezicha , David T. Trana , Edward Guilmettec, Gene ID: Human(3706) Summary: Regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4.
Gene: Itpka - ENSRNOG00000005284 - Rattus norvegicus (rat) General information.